Guilty by Association: Small-World Problem Emphasizes Critical Need for Business Strategies in Response to the Foreign Intelligence Surveillance Act

Article published in the Michigan State Law Review

GIS, GPS, and Remote Sensing Technologies in Extension Services: Where to Start, What to Know

The rapid development and integration of spatial technologies such as Geographic Information Systems, the Global Positioning System, and remote sensing, have created many new tools for Extension professionals, but have also widened the digital divide, leaving many with little understanding of the technology and potential applications. This article presents examples of Extension-related applications of GIS-GPS-RS technologies and discusses how to go about learning more and determining if these technologies would be useful. Examples and recommendations are taken from the literature and from the authors\u27 own experience

Research on the International Space Station - An Overview

The International Space Station (ISS) celebrates ten years of operations in 2008. While the station did not support permanent human crews during the first two years of operations November 1998 to November 2000 it hosted a few early science experiments months before the first international crew took up residence. Since that time and simultaneous with the complicated task of ISS construction and overcoming impacts from the tragic Columbia accident science returns from the ISS have been growing at a steady pace. As of this writing, over 162 experiments have been operated on the ISS, supporting research for hundreds of ground-based investigators from the U.S. and international partners. This report summarizes the experimental results collected to date. Today, NASA's priorities for research aboard the ISS center on understanding human health during long-duration missions, researching effective countermeasures for long-duration crewmembers, and researching and testing new technologies that can be used for future exploration crews and spacecraft. Through the U.S. National Laboratory designation, the ISS is also a platform available to other government agencies. Research on ISS supports new understandings, methods or applications relevant to life on Earth, such as understanding effective protocols to protect against loss of bone density or better methods for producing stronger metal alloys. Experiment results have already been used in applications as diverse as the manufacture of solar cell and insulation materials for new spacecraft and the verification of complex numerical models for behavior of fluids in fuel tanks. A synoptic publication of these results will be forthcoming in 2009. At the 10-year point, the scientific returns from ISS should increase at a rapid pace. During the 2008 calendar year, the laboratory space and research facilities were tripled with the addition of ESA's Columbus and JAXA's Kibo scientific modules joining NASA's Destiny Laboratory. All three laboratories, together with external payload accommodations, support a wide variety of research racks and science and technology experiments. In 2009, the number of crewmembers will increase from three to six, greatly increasing the time available for research. The realization of the international scientific partnership provides new opportunities for scientific collaboration and broadens the research potential on the ISS. Engineers and scientists from around the world are working together to refine their operational relationships and build from their experiences conducting early science to ensure maximum utilization of the expanded capabilities aboard ISS. This paper will summarize science results and accomplishments, and discuss how the early science utilization provides the foundation for continuing research campaigns aboard the ISS that will benefit future exploration programs

Reducing Outpatient Antibiotic Resistance: A Quasi-Experimental Study

Approved May 2017 by the faculty of UMKC in partial fulfillment of the requirements for the degree of Doctor of Nursing PracticeApproximately 50% of antibiotics prescribed are not necessary, nevertheless in the United States among the many outpatient prescriptions, few are more widely prescribed than antibiotics. The inappropriate use of antibiotics to treat non-bacterial infections has been largely responsible for the emergence of antibiotic resistance. The purpose of this DNP project was to evaluate the effect of an antibiotic stewardship program on urgent care providers’ antibiotic prescribing for acute respiratory infections and to analyze providers’ awareness and beliefs regarding antibiotic use and resistance. A quasi-experimental study was conducted among a convenience sample of eight urgent care providers who received a one hour theory-based intervention program on antibiotic prescribing. Outcomes measured included provider antibiotic prescribing rates pre- and post-intervention, differences in antibiotic prescribing among the providers, and provider attitude and knowledge regarding antibiotic prescribing and resistance. The antibiotic prescribing rate decreased from 30% to 20% post-intervention, p =. 078. The odds ratio of nurse practitioners preferring not to prescribe antibiotics pre-intervention was 3.273 (p = .001) and post-intervention 4.155 (p = < .0005) times more than physicians. Within their setting, 84.43% believed antibiotics are overused, and 92.25% believed antibiotic resistance is a problem. Implementation of an outpatient antibiotic stewardship program is necessary to decrease inappropriate antibiotic prescribing, slow progression of antibiotic resistance, and decrease healthcare costs associated with this world-wide public health problem

Guilty by Association: Small-World Problem Emphasizes Critical Need for Business Strategies in Response to the Foreign Intelligence Surveillance Act

Article published in the Michigan State Law Review

Genetic determinants of cerebral edema in severe traumatic brain injury: A pilot study of the role of CACNA1 and AQP4 gene mutations

Cerebral edema is the one of the most significant predictors of poor outcome after traumatic brain injury. It is still unclear what the pathophysiological and cellular mechanisms and predictors of post-traumatic edema are. The exponential growth in genetic information has opened an avenue for investigation in traumatic brain injury and implicated specific genes in the pathophysiology of post-traumatic injury edema. Two examples are the Aquaporin-4 and CACNA1 genes, which respectively encode water and calcium channels. The Aquaporin-4 gene on chromosome 18q11.2-12.1 encodes the Aquaporin-4 protein (AQP4) water channel. AQP4 is one of the bidirectional high capacity water channels that is primarily expressed in astrocytic foot processes in the central nervous system at the blood-brain barrier and is thought to be critical for brain water homeostasis. Experimental studies showed that AQP4 deficient mice had significantly reduced cerebral edema and better survival in a water intoxication model. The CACNA1 gene on chromosome 19p13 encodes the a1A subunit of a neuronal calcium channel. Patients with Familial Hemiplegic Migraine and delayed fatal cerebral edema and seizuresfrom minor trauma have been found to have mutations in CACNA1, which are hypothesized to enhance development of cytotoxic edema. A missense mutation is reported to enhance risk of delayed fatal cerebral edema. Hypothesis: The CACNA1 gene missense mutation S218L and AQP4 polymorphisms will be over-represented in patients with post-traumatic cerebral edema. Our Specific Aim is to perform full exon sequence analysis of these two genes in 20 well-defined cases of excessive cerebral edema. Our long term goal is to systematically investigate genetic variants as determinants of risk of excessive cerebral edema. It is hoped that this will further elucidate secondary mechanisms of injury specifically in the formation of post-traumatic edema and lead to targeted therapies in the future

California Drought: Hydrological and Regulatory Water Supply Issues

This report provides a summary of California's 2012-2015 drought including: comparisons, where applicable, to previous droughts; a summary of the key regulatory requirements that at certain times limit water deliveries (or exports) from the San Joaquin and Sacramento Rivers' Delta; and a brief discussion of California water rights with their relation to different types of federal contracts and their associated water allocations